ethyl 2-(ethoxymethylidene)-4,4,4-trifluoro-3-oxobutanoate - Names and Identifiers
Name | ethyl 2-(ethoxymethylene)-4,4,4-trifluoro-3-oxobu
|
Synonyms | ETHYL 3-ETHOXY-2-(2,2,2-TRIFLUOROACETYL)ACRYLATE ethyl 3-ethoxy-2-(2,2,2-trifluoroacetyl)acrylate ethyl 2-(ethoxymethylene)-4,4,4-trifluoro-3-oxobu ETHYL ETHOXYMETHYLENE-3-OXO-4,4,4-TRIFLUOROBUTYRATE Ethyl ethoxymethylene-3-oxo-4,4,4-trifluoro-butyrate ETHYL 2-(ETHOXYMETHYLENE)-4,4,4-TRIFLUOROACETOACETATE Ethyl 2-(Ethoxymethylene)-4,4,4-Trifluoroacetoacetate ETHYL 2-(ETHOXYMETHYLENE)-4,4,4-TRIFLUORO-3-OXOBUTYRATE Ethyl 2-(ethoxymethylene)-4,4,4-trifluoro-3-oxobutyrate ethyl 2-(ethoxymethylidene)-4,4,4-trifluoro-3-oxobutanoate ethyl (2E)-2-(ethoxymethylene)-4,4,4-trifluoro-3-oxo-butanoate ethyl (2Z)-2-(ethoxymethylidene)-4,4,4-trifluoro-3-oxobutanoate ethyl 2-(ethoxymethylene)-4,4,4-trifluoro-3-oxobutyrate,mixture of cis and trans
|
CAS | 571-55-1
|
EINECS | 611-474-9 |
InChI | InChI=1/C9H11F3O4/c1-3-15-5-6(8(14)16-4-2)7(13)9(10,11)12/h5H,3-4H2,1-2H3/b6-5+ |
InChIKey | XNGGOXOLHQANRB-WAYWQWQTSA-N |
ethyl 2-(ethoxymethylidene)-4,4,4-trifluoro-3-oxobutanoate - Physico-chemical Properties
Molecular Formula | C9H11F3O4
|
Molar Mass | 240.18 |
Density | 1.235g/mLat 25°C(lit.) |
Boling Point | 80-82°C1mm Hg(lit.) |
Flash Point | 220°F |
Vapor Presure | 0.181mmHg at 25°C |
Appearance | clear liquid |
Specific Gravity | 1.239 |
Color | Light orange to Yellow to Green |
Storage Condition | 2-8°C |
Refractive Index | n20/D 1.429(lit.) |
MDL | MFCD02677683 |
ethyl 2-(ethoxymethylidene)-4,4,4-trifluoro-3-oxobutanoate - Risk and Safety
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin.
R22 - Harmful if swallowed
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S23 - Do not breathe vapour.
|
WGK Germany | 3 |
HS Code | 29171900 |
Hazard Class | IRRITANT |
ethyl 2-(ethoxymethylidene)-4,4,4-trifluoro-3-oxobutanoate - Introduction
Ethyl 2-(ethoxymethylene)-4,4,4-trifluoro-3-oxobu, also known as ethyl 2-(ethoxymethylene)-4,4, 4-trifluoro-3-oxobutyrate, the chemical formula is C8H7F3O4. It is an organic compound with the following properties:
1. Appearance: It is a colorless liquid with a special smell.
2. solubility: soluble in most organic solvents, such as ethanol, ether and dimethyl sulfoxide.
3. Melting point: Its melting point range is -40°C to -36°C.
4. Boiling point: Its boiling point is 100°C to 102°C.
ethyl ethyl 2-(ethoxymethylene)-4,4, 4-trifluororo-3-oxobu (EEOT) is commonly used as a reagent and intermediate, and has certain applications in organic synthesis. Here are some common uses:
1. synthetic drugs: EEOT can be used to synthesize certain drugs, such as acetylcholinesterase inhibitors and cholinergic receptor agonists.
2. Materials Science: EEOT can be used to prepare polymer materials, such as polyurethane and polyester.
3. Surfactant: EEOT has a low surface tension and can be used as a surfactant and emulsifier.
EEOT is prepared by the condensation reaction of ethoxyethylene ether and 2-fluoroethanone under alkaline conditions. During the preparation process, attention should be paid to safe operation, avoid contact with skin and eyes, and maintain good ventilation conditions. When handling or storing EEOT, high temperatures and sources of ignition should be avoided to prevent its decomposition or dangerous reactions.
Last Update:2024-04-09 21:21:28